Flavonoids: Apigenin In Cannabis

Flavonoids: Apigenin In Cannabis

Flavonoids: Apigenin In Cannabis

Apigenin is a flavonoid that is found in various plants, including cannabis. It is one of the most common flavonoids in the human diet and is present in many fruits, vegetables, and herbs. In cannabis, apigenin is present in low concentrations, but it has been found to have potential therapeutic effects.

Like other flavonoids, apigenin is a powerful antioxidant, which means that it can help protect cells from damage caused by free radicals. Free radicals are molecules that are generated by various metabolic processes in the body, as well as by exposure to environmental toxins and radiation. They can cause oxidative stress, which can lead to a variety of health problems, including inflammation, cell damage, and chronic diseases such as cancer and heart disease. By neutralizing free radicals, apigenin may help prevent or reduce the risk of these health problems.

In addition to its antioxidant properties, apigenin has also been shown to have anti-inflammatory and anti-cancer effects. A 2017 study published in the journal “Molecules” found that apigenin was able to inhibit the growth of cancer cells and induce apoptosis (programmed cell death) in vitro. The study also found that apigenin had anti-inflammatory effects, which could help reduce the risk of chronic diseases.

Furthermore, apigenin has been shown to have potential anxiolytic (anxiety-reducing) effects. A 2012 study published in the journal “Phytotherapy Research” found that apigenin was able to reduce anxiety in mice in a dose-dependent manner. The researchers suggest that apigenin may be a potential treatment for anxiety disorders in humans.

It’s worth noting that while apigenin is found in cannabis plants, it is not psychoactive and does not produce the “high” associated with THC, another compound found in the plant. Furthermore, cannabis plants typically contain very low concentrations of apigenin, which means that it is not currently used in medical or therapeutic applications. However, its potential as an antioxidant, anti-inflammatory, anti-cancer, and anxiolytic agent has sparked interest in further research and development.


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